Factory Price Pharmacological Properties 98% N-Acetyl-L-Cysteine Ethyl Ester (NACET)

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >98%
• Appearance: Powder
• Color: White
• Delivery Time: Prompt Shipment
• Sample: Free for Test
• Transport Package: Carton or Drum
• Specification: 25KG
• Trademark: AWI
• Origin: China
• Production Capacity: 500000mt/Year

Product Description

Factory price pharmacological properties 98% N-Acetyl-L-cysteine ethyl ester (NACET) 




What is NACET/N-Acetyl CysteineEthyl Ester?

Recent large clinical trials failed to confirm the supposed beneficial effects of N-acetylcysteine (NAC) in preventing oxidativestress-related diseases. This may be due to its low bioavailability. We thought that esterification of the carboxyl group of NAC to produce N-acetylcysteine ethyl ester (NACET) would drastically increase the lipophilicity of NAC, thus greatly improving its pharmacokinetics. In the present work, we report on representative chemical, pharmacological and anti-oxidant properties of NACET, especially in direct comparison with its congener NAC. We found that NACET is rapidly absorbed in rats after oral administration but reaches very low concentrations in plasma. This is due to a unique feature of NACET: it rapidly enters the cells where it is trapped being transformed into NAC and cysteine. After oral treatment, NACET (but not NAC) was able to increase significantly the glutathione content of most tissues examined, brain included, and to protect from paracetamol intoxication in the rat. NACET has also the unique feature to accumulate in human erythrocytes where it behaves as a potent protector against hydroperoxide-induced oxidative damage. Our study shows that being able to enter cells and to produce NAC and cysteine, NACET increases circulating hydrogen sulfide (H(2)S), thus representing a good candidate for the oral use as an H(2)S producer, with clear advantages over NAC. NACET has the potential to substitute NAC as a mucolytic agent, as a paracetamol antidote and as a GSH-related antioxidant.

 

Specification

Function :

1. N-acetyl Cysteine has an effective detoxification.
2. N-acetyl Cysteine can effectively prevent and treat radiation injury.
3. N-acetyl Cysteine can remove the skin melanin itself, change the nature of the skin itself, the skin becomes natural whitening.
It is a kind of ideal natural whitening cosmetics.
4. N-acetyl Cysteine can improve the symptoms of inflammation and skin allergies.
5. N-acetyl Cysteine on horny skin disease is also effective hypertrophy.
6. N-acetyl Cysteine has a function to prevent biological aging

1.Used as bread fermentation promoter, preservative;
2.Accelerate the formation of gluten, prevent aging; Natural juice can prevent the oxidation and browning of Vc;
3.Aromatic acidosis,prevention of radiation damage,reatment of bronchitis and phlegm;
4.Food additive.

Packing & Delivery

 

 

25kgs bags with PE bag liner or following customers' demands.

Company Profile

 

 

AWI is a world's leading developer of functional ingredients to the Nutritional supplement,Health food and beverage,Pharmaceutical and Personal care industries. Together with our professional experience and best-in-class customer service, we make the purchasing process simple, strategic and successful!

FAQ

1. who are we?
We are based in Anhui, China, start from 2016,sell to North America(26.00%),South America(13.00%),Oceania(12.00%),Western Europe(8.00%),Eastern Europe(8.00%),Southeast Asia(8.00%),Northern Europe(7.00%),South Asia(6.00%),Southern Europe(6.00%),Eastern Asia(6.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Amino acids,Food ingredients,Vitamins,Plant extracts,Feed additives

4. why should you buy from us not from other suppliers?
AWI is a world's leading developer of functional ingredients to the Nutritional supplement,Health food and beverage,Pharmaceutical and Personal care industries.

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,FAS,CIP,FCA,CPT,DEQ,DDP,DDU,Express Delivery,DAF,DES;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,D/P D/A,MoneyGram,Credit Card,PayPal,Western Union;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian